[Central corneal thickness, endothelial characteristics and intraocular pressure in congenital cataract extracted eyes]

To investigate central corneal thickness [CCT], endothelial cell characteristics and intraocular pressure [IOP] in congenital cataract extracted eyes and to compare the results with eyes of normal age and sex matched controls. CCT and IOP measurements and specular microscopy were performed in 31 eyes of 17 cases of extracted congenital cataracts and 40 eyes of 20 age and sex matched subjects as control group. Mean of three pachymetry measurements of the central cornea was taken as CCT. IOP was measured using an applanation tonometer. Mean CCT was 632 +/- 45 microm in cataract extracted eyes vs 546 +/- 33 microm in the control eyes [P<0.001, independent t test and Mann Whitney test]. There was no significant difference in cell count, coefficient of variation, and mean cell area of the corneal endothelial cells between the two groups. Mean IOP was 22.1 +/- 3.9 mmHg in the cataract extracted eyes and 14.0 +/- 1.6 mmHg in the control group [P<0.001, independent t test]. Although the cornea was clinically clear and there was no significant difference in endothelial characteristics of congenital cataract extracted eyes compared to normal controls, central corneal thickness in operated eyes was significantly greater than that of controls. To differentiate actual glaucoma from artifactual IOP increase, CCT measurement should strongly be considered in these patients

[Measurement of intraocular pressure using schiotz vs tono-pen tonometers in patients with primary congenital glaucoma]

To compare the Tono-pen and Schiotz tonometers in measurement of intraocular pressure [IOP] in patients with primary congenital glaucoma. This study was conducted on 38 eyes of 20 patients with primary congenital glaucoma. All measurements were performed under general anesthesia. One minute after receiving Halothane 3% IOP was determined by Tono-pen and then by Schiotz tonometers. Data were analyzed by regression analysis and Bland-Altman bias plot. Mean age of patients was 19.4 +/- 14.5 months and 15 [75%] of them were male. Glaucoma was bilateral in 18 [90%] and unilateral in 2 [10%] subjects. Mean IOP measured by Tono-pen and Schiotz tonometers was 19.39 +/- 8.51 and 18.84 +/- 8.9 mmHg, respectively. These tonometers had good concordance in determination of IOP in primary congenital glaucoma according to the results of regression analysis and Bland-Altman bias plot. Considering the sample size of this study, the Tono-pen and Shiotz tonometers are highly concordant regarding intraocular pressure measurement in children with primary congenital glaucoma